## 进入参考基因组目录
mkdir -p $HOME/database/GRCh38.105
cd $HOME/database/GRCh38.105

## 下载基因组
## 一般选择primary assembly，没有的话可以选择toplevel
nohup wget -c https://ftp.ensembl.org/pub/release-105/fasta/homo_sapiens/dna/Homo_sapiens.GRCh38.dna.primary_assembly.fa.gz > dna.log &

## 下载转录组序列
nohup wget -c http://ftp.ensembl.org/pub/release-105/fasta/homo_sapiens/cdna/Homo_sapiens.GRCh38.cdna.all.fa.gz >rna.log &

## 下载基因组注释文件
nohup wget -c http://ftp.ensembl.org/pub/release-105/gtf/homo_sapiens/Homo_sapiens.GRCh38.105.chr.gtf.gz >gtf.log &

nohup wget -c http://ftp.ensembl.org/pub/release-105/gff3/homo_sapiens/Homo_sapiens.GRCh38.105.chr.gff3.gz >gff.log&